Why exactly does God have a problem with ity?

I want to respond to one of your premises. The Catholic church DOES maintain that if couples aren't even open to considering children should NOT marry. And if in a marriage it is ascertained that one of the persons is sterile - that is sufficient grounds for an annulment. "...then why would God create organisms that are genetically coded...etc." It's like a birth defect. Children are born everyday with some kind of defect - and this is one of them.